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BAY-218
Item number: TGM-T5622-100mg
Description: BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist with an IC50 of 39.9 nM in a human cell line. Target: Aryl Hydrocarbon Receptor, AhR. Smiles: C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1. References: Ilona Gutcher, Christina Kober, Lars Roese,et al.Abstract 1288:...
| Keywords: | AHR antagonist 1 |
| Application: | AhR antagonist |
| CAS | 2162982-11-6 |
| MW: | 401.82 D |
From 34.00€
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BAY-218
Item number: Cay37583-10
BAY-218 is an aryl hydrocarbon receptor antagonist (AhR, IC50 = 39.9 nM). Preincubation with BAY-218 (1 µM) decreases AhR nuclear translocation induced by aflatoxin B1 (Cay-11293) in L-02 hepatocytes and TK6 lymphoblasts. BAY-218 (30 mg/kg), alone and in combination with an anti-PD-L1 antibody, reduces tumor growth...
| Keywords: | BAY-2335218, 6-(4-chlorophenyl)-2-(3-fluorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-3-oxo-4-pyridazinecarboxamide |
| Application: | AhR antagonist |
| CAS | 2162982-11-6 |
| MW: | 401.8 D |
From 92.00€
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