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PD 174265
Item number: TGM-T28339-100mg
Description: PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM. Target: EGFR. Smiles: CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1. References: Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2,...
| Keywords: | PD-174265, N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide, PD174265 |
| Application: | Cell-permeable EGFR inhibitor |
| CAS | 216163-53-0 |
| MW: | 371.23 D |
From 50.00€
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PD 174265
Item number: Cay17649-1
PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM). It is effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively). The action of PD 174265 is reversible,...
| Keywords: | N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-propanamide |
| Application: | Cell-permeable EGFR inhibitor |
| CAS | 216163-53-0 |
| MW: | 371.2 D |
From 92.00€
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