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Blu-782
Blu-782

Item number: TGM-T8108-100mg

Description: Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM). Target: ALK. Smiles: CCOC1(CCN(CC1)C(C)C)c1ccc(nc1)-c1cc2c(ccnn2c1)N1CCN(CC1)C(=O)O[C@@H]1CCOC1. References: ALK2-IN-1
Keywords: ALK2-IN-1
Application: Targets activin receptor type-1 [EC:2.7.11.30] (ACVR1, ALK2)
CAS 2141955-96-4
MW: 562.7 D
From 74.00€ *
Review
BLU-782
BLU-782

Item number: Cay35490-1

BLU-782 is an inhibitor of activin receptor-like kinase 2 (ALK2) containing an arginine-to-histidine substitution mutation at position 206 (ALK2R206H), an activating mutation found in patients with fibrodysplasia ossificans progressiva (FOP), which is characterized by progressive heterotopic ossification, or diffuse...
Keywords: Activin Receptor-like Kinase 2 Inhibitor 1, ALK2-IN-1, Fidrisertib,...
Application: ALK2(R206H) inhibitor
CAS 2141955-96-4
MW: 562.7 D
From 77.00€ *
Review