- Search results for 2140301-96-6
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2 products were found matching "2140301-96-6"!
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Item number: TGM-T12427-100mg
Description: Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively). Target: JAK. Smiles: Cc1ccc(cc1)S(O)(=O)=O.Cn1cc(Nc2nccc(n2)N2CC3CCC(C2)N3C(=O)[C@@H]2CC2(F)F)cn1. References: Fensome A, et al. Dual Inhibition of TYK2...
Keywords: | PF-06700841 P-Tosylate |
Application: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
CAS | 2140301-96-6 |
MW: | 561.6 D |
From 31.00€
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Item number: Cay26125-5
PF-06700841 is an inhibitor of JAK1 and tyrosine kinase 2 (TYK2, IC50s = 17 and 23 nM, respectively). It is selective for JAK1 and TYK2 over JAK2 and JAK3 (IC50s = 77 and 6,494 nM, respectively). PF-06700841 selectively inhibits IFN-alpha/STAT3 signaling over erythropoietin/STAT5 signaling in human whole blood...
Keywords: | [(1S)-2,2-difluorocyclopropyl][3-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-3,8-diazabicyclo[3.2.1]oct-8-yl]-meth... |
Application: | JAK1 / TYK2 inhibitor |
CAS | 2140301-96-6 |
MW: | 561.6 D |
From 44.00€
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