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Vatalanib dihydrochloride
Item number: TGM-T6720-100mg
Description: Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4. Target: VEGFR, Apoptosis, PDGFR. Smiles: Cl.Cl.Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1. References: Wood JM, et al. Cancer Res....
| Keywords: | ZK-222584 dihydrochloride, CGP-797870 dihydrochloride, CGP-79787 dihydrochloride, Vatalanib 2HCl, PTK787 dihydrochloride,... |
| Application: | VEGFR inhibitor |
| CAS | 212141-51-0 |
| MW: | 419.73 D |
From 42.00€
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Vatalanib (hydrochloride)
Item number: Cay14868-10
Vatalanib is an antagonist of the VEGF receptors, inhibiting the receptor tyrosine kinase activities of VEGFR1 (Flt1), VEGFR2 (KDR), and VEGFR3 (Flt4) with IC50 values of 77, 37, and 190 nM, respectively. It less potently inhibits PDGF and c-Kit (IC50 = 600 and 700 nM) and has no effect on a large panel of...
| Keywords: | CGP 79787, PTK/ZK, PTK787, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine, dihydrochloride |
| Application: | VEGFR inhibitor |
| CAS | 212141-51-0 |
| MW: | 419.7 D |
From 70.00€
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Vatalanib Dihydrochloride...
Item number: V2120-70A.25
Vatalanib is a potent, selective, orally active inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC50=77nM) and VEGFR-2 (FLK-1/KDR, IC50=37nM), with slightly higher potency against the latter. At higher concentrations, other tyrosine kinases are also inhibited, including PDGFR-b (IC50=580nM), c-KIT...
| CAS | 212141-51-0 |
| MW: | 419.73 |
216.00€
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Vatalanib dihydrochloride
Item number: LKT-V0376.1
Protein Kinase inhibitor under research for the treatment of solid tumors.
| CAS | 212141-51-0 |
| MW: | 419.73 D |
From 81.00€
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