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Gliclazide
Item number: TGM-T1527-1g
Description: Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the pancreas to release insulin. Target: Potassium Channel. Smiles: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1. References: Mamputu JC, Renier G. J...
| Keywords: | SE1702, S1702 |
| Application: | Targets ATP-binding cassette subfamily C (CFTR/MRP) member 8 (ABCC8, SUR1) |
| CAS | 21187-98-4 |
| MW: | 323.41 D |
From 45.00€
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Gliclazide
Item number: Cay25503-1
Gliclazide is a sulfonylurea and an inhibitor of pancreatic beta-cell ATP-sensitive potassium (KATP) channels (IC50 = 184 nM for murine beta-cells). It is selective for pancreatic beta-cell over cardiac and arterial smooth muscle cell KATP channels (IC50s = 19.5 and 37.9 µM, respectively). Gliclazide (5 µM)...
| Keywords: | N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-benzenesulfonamide |
| Application: | Antidiabetic agent, sulfonamide hypoglycemic, sulfonylurea receptor agonist |
| CAS | 21187-98-4 |
| MW: | 323.4 D |
From 44.00€
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Gliclazide
Item number: LKT-G4532.1
Sulfonylurea, SUR1 antagonist.
| Keywords: | Diamicron, Glimicron, Nordialex, N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]- carbonyl]-4-methylbenzenesulfonamide |
| Application: | Sulfonylurea receptor 1 agonist |
| CAS | 21187-98-4 |
| MW: | 323.41 D |
From 92.00€
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