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WHI-P154
Item number: TGM-T1985-100mg
Description: WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor. Target: VEGFR, JAK, Apoptosis, EGFR, Src. Smiles: COc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1OC. References: Changelian PS,Blood, 2008, 111(4), 2155-2157.
| Keywords: | Jak3 inhibitor ii |
| Application: | JAK3 inhibitor |
| CAS | 211555-04-3 |
| MW: | 376.2 D |
From 37.00€
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WHI-P154
Item number: Cay16178-10
WHI-P154 is a quinazoline derivative that exhibits immunosuppressive effects by selectively inhibiting JAK3 (IC50 = 1.8 µM versus IC50s > 10 µM for JAK1 and JAK2). It has been reported to inhibit additional kinases including EGFR (IC50 = 4 nM) and VEGFR as well as the non-receptor tyrosine kinases, Abl, Lck, and...
| Keywords: | JAK3 Inhibitor II, Janus-Associated Kinase 3 Inhibitor II, 2-bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
| Application: | JAK3 inhibitor |
| CAS | 211555-04-3 |
| MW: | 376.2 D |
From 111.00€
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