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Item number: TGM-T6048-100mg

Description: Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 µM), increases the plasma HDL cholesterol. Target: CETP. Smiles: CCC(CC)CC1(CCCCC1)C(=O)Nc1ccccc1SC(=O)C(C)C. References: Niesor EJ, et al. J Lipid Res. 2010, 51(12), 3443-3454.

Keywords:	JTT-705, RO4607381
Application:	Targets cholesteryl ester transfer protein (CETP)
CAS	211513-37-0
MW:	389.59 D

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Dalcetrapib

Item number: Cay89450-1

Cholesteryl ester transfer protein (CETP) is an exchange protein which transfers cholesteryl esters from HDL to VLDL, IDL, and LDL in exchange for triglycerides. Dalcetrapib is an inhibitor of CETP that exhibits an IC50 value of 9 µM for plasma CETP in rabbits. Inhibition of CETP by dalcetrapib in rabbits given an...

Keywords:	JTT-705, S-[2-[[[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino]phenyl]propanethioic acid, 2-methyl ester
Application:	Cholesteryl ester transfer protein inhibitor
CAS	211513-37-0
MW:	389.6 D

From 54.00€ *

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