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Item number: Cay30814-1

Sobetirome is an agonist of thyroid hormone receptor beta (TRbeta, EC50 = 7 nM in a reporter assay). It selectively binds to TRbeta over TRalpha with Kd values of 0.1 and 1.8 nM, respectively. Sobetirome (97 nmol/kg, i.p.) increases hepatic levels of the HDL receptor SR-B1 and serum levels of C4, a marker of...

Keywords:	GC-1, QRX 431, 2-[4-[[4-hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]-acetic acid
Application:	Thyroid hormone receptor beta (Trbeta) agonist
CAS	211110-63-3
MW:	328.4 D

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