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Item number: Cay12086-5

Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. CPTH2 inhibits the HAT activity of Gcn5 both in vitro and in vivo, reducing histone H3K14 acetylation at a concentration of 0.8 mM. It...

Keywords:	2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone, monohydrochloride
Application:	HAT inhibitor
CAS	2108899-91-6
MW:	328.3 D

From 133.00€ *

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CPTH2 (hydrochloride) (357649-93-5 free base)

Item number: TGM-T22693-10mg

Description: CPTH2 is an inhibitor of the HAT activity of Gcn5. Target: Others. Smiles: Cl.ClC=1C=CC(=CC1)C=2N=C(SC2)NN=C3CCCC3

Keywords:	CPTH2 (hydrochloride)
Application:	HAT inhibitor
CAS	2108899-91-6
MW:	328.26 D

From 242.00€ *

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