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CP 424174
Item number: TGM-T8828-100mg
Description: CP 424174 is an inhibitor of IL-1beta post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1beta. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable. Target: IL Receptor. Smiles: CC(C)c1cc(Cl)cc(C(C)C)c1NC(=O)NS(=O)(=O)c1cccc(c1)C(C)(C)O. References:...
| Application: | Stimulus-coupled IL-1beta post-translational processing inhibitor |
| CAS | 210825-31-3 |
| MW: | 452.99 D |
From 40.00€
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CP 424,174
Item number: Cay29675-1
CP 424,174 is an inhibitor of stimulus-coupled IL-1beta post-translational processing. It inhibits ATP-induced proteolytic cleavage of pro-IL-1beta, measured by secretion of the 17 kDa mature form of IL-1beta, in LPS-primed human blood-derived monocytes when used at concentrations of 0.5 and 2.5 µM. CP 424,174...
| Keywords: | N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-benzenesulfonamide |
| Application: | Stimulus-coupled IL-1beta post-translational processing inhibitor |
| CAS | 210825-31-3 |
| MW: | 453 D |
From 43.00€
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