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Item number: Cay29675-1

CP 424,174 is an inhibitor of stimulus-coupled IL-1beta post-translational processing. It inhibits ATP-induced proteolytic cleavage of pro-IL-1beta, measured by secretion of the 17 kDa mature form of IL-1beta, in LPS-primed human blood-derived monocytes when used at concentrations of 0.5 and 2.5 µM. CP 424,174...

Keywords:	N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-benzenesulfonamide
Application:	Stimulus-coupled IL-1beta post-translational processing inhibitor
CAS	210825-31-3
MW:	453 D

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