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N-Butyldeoxynojirimycin (hydrochloride)
N-Butyldeoxynojirimycin (hydrochloride)

Item number: Cay21065-1

NB-DNJ is an iminosugar that inhibits UDP-glucose ceramide glucosyltransferase and beta-glucosidase 2 (IC50s = 32 and 81 µM, respectively, for the rat recombinant enzymes). It also increases the activity of wild-type acid beta-glucosidase, as well as the S364R, N370S, V15M, or M123T mutants, in COS-7 cells...
Keywords: Miglustat, NB-DNJ, 1-butyl-2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol, monohydrochloride
Application: Glucosylceramide synthase inhibitor
CAS 210110-90-0
MW: 255.7 D
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