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Item number: TGM-T5439-5mg

Description: BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells. Target: Epigenetic Reader Domain, PROTACs. Smiles:...

Application:	BRD4 degradation driving PROTAC
CAS	2098836-45-2
MW:	972.68 D

1,099.00€ *

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AT-1

Item number: Cay33265-1

AT-1 is a proteolysis-targeting chimera (PROTAC) that contains the bromodomain and extra terminal (BET) domain-containing protein inhibitor (+)-JQ1 (Cay-11187) conjugated to PROTAC building block VH ligand 032 (Cay-39982). It selectively degrades bromodomain-containing protein 4 (BRD4) over BRD3 and BRD2 in HeLa...

Keywords:	(4R)-N-acetyl-3-[[6-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]...
Application:	BRD4 degradation driving PROTAC
CAS	2098836-45-2
MW:	972.7 D

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