- Search results for 2097002-61-2
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3 products were found matching "2097002-61-2"!
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Item number: TGM-T7435-100mg
Description: Selitrectinib (LOXO-195) is a potent and selective inhibitor of receptor tyrosine kinases TRK (TrkA and TrkC) with IC50 values of 0.6 nM and <2.5 nM, respectively. Target: Trk receptor. Smiles: [H][C@]12CCCN1c1ccn3ncc(C(=O)N[C@H](C)CCc4ncc(F)cc24)c3n1. References: Drilon A , Nagasubramanian R , Blake J...
Keywords: | LOXO-195 |
Application: | TrkA / TrkC inhibitor |
CAS | 2097002-61-2 |
MW: | 380.42 D |
From 34.00€
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Item number: Cay27062-1
LOXO-195 is an inhibitor of the receptor tyrosine kinases TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 value of 1.9 nM. It selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = =5 nM) over Trk fusion-negative...
Keywords: | Selitrectinib,... |
Application: | TrkA / TrkC inhibitor |
CAS | 2097002-61-2 |
MW: | 380.4 D |
From 35.00€
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Item number: LKT-L589938.1
Keywords: | LOXO195, 0J45910S3X, Selitrectinib,... |
Application: | TrkA / TrkC inhibitor |
CAS | 2097002-61-2 |
MW: | 380.43 D |
From 123.00€
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