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Selitrectinib
Selitrectinib

Item number: TGM-T7435-100mg

Description: Selitrectinib (LOXO-195) is a potent and selective inhibitor of receptor tyrosine kinases TRK (TrkA and TrkC) with IC50 values of 0.6 nM and <2.5 nM, respectively. Target: Trk receptor. Smiles: [H][C@]12CCCN1c1ccn3ncc(C(=O)N[C@H](C)CCc4ncc(F)cc24)c3n1. References: Drilon A , Nagasubramanian R , Blake J...
Keywords: LOXO-195
Application: TrkA / TrkC inhibitor
CAS 2097002-61-2
MW: 380.42 D
From 34.00€ *
Review
LOXO-195
LOXO-195

Item number: Cay27062-1

LOXO-195 is an inhibitor of the receptor tyrosine kinases TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 value of 1.9 nM. It selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = =5 nM) over Trk fusion-negative...
Keywords: Selitrectinib,...
Application: TrkA / TrkC inhibitor
CAS 2097002-61-2
MW: 380.4 D
From 35.00€ *
Review
LOXO-195
LOXO-195

Item number: LKT-L589938.1

Keywords: LOXO195, 0J45910S3X, Selitrectinib,...
Application: TrkA / TrkC inhibitor
CAS 2097002-61-2
MW: 380.43 D
From 123.00€ *
Review