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Lipid-based Drug Delivery Tools from Cayman Chemical

Lipid-based drug delivery (LBDD) systems, such as LNPs, liposomes, and solid lipid nanoparticles (SLNs), are customizable platforms for the targeted delivery of pharmaceuticals and other therapeutic agents to cells and tissues. LBDD overcomes obstacles associated with conventional therapeutic formulations by encapsulating bioactive molecules in a lipid vesicle, which increases their bioavailability, distribution, and plasma half-life, and decreases systemic toxicity induced by off-target activity. The versatility of LBDD formulations is achievable in part through the diversity of lipids available for these applications. Our partner Cayman Chemical offers high-quality lipid components that can be used to build lipid particles as research tools, as well LNP Exploration Kits and Custom Lipid Synthesis to support preclinical research programs.

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Blog Article: Lipid-based Drug Delivery Development - Part 1
Blog Article: Lipid-based Drug Delivery Development - Part 2
Caymans Guide to Lipid Nanoparticle Formulation

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Lipid-based Drug Delivery Tools

SM-102

Item number: Cay33474-50

SM-102 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of luciferase mRNA in SM-102-containing LNPs induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development...

Keywords:	8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester
Application:	Ionizable amino lipid
CAS	2089251-47-6
MW:	710.2 D

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