Description: VBIT-12 is a potent inhibitor of VDAC1. Target: VDAC. Smiles: N(C1(C(NCC(O)=O)=O)CCN(CC=2C3=C(C=CC2)C=CC=C3)CC1)C4=CC=CC=C4. References: Shoshan-Barmatz V, et al. VDAC1, mitochondrial dysfunction, and Alzheimer's disease. Pharmacol Res. 2018 May,131:87-101.

VBIT-12 is a voltage-dependent anion channel 1 (VDAC1) inhibitor. It inhibits VDAC1 conductance in synthetic lipid membranes containing purified rat VDAC1 when used at concentrations ranging from 20 to 100 µM.Formal Name: N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-glycine. CAS Number:...