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JNJ-64619178
JNJ-64619178

Item number: TGM-T15624-10mg

Description: JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer. Target: Histone Methyltransferase. Smiles: Nc1nc2cc(CC[C@H]3C[C@H]([C@H](O)[C@@H]3O)n3ccc4c(N)ncnc34)ccc2cc1Br. References:...
Application: PRMT5 inhibitor
CAS 2086772-26-9
MW: 483.36 D
From 81.00€ *
Review
JNJ-64619178
JNJ-64619178

Item number: Cay29231-1

JNJ-64619178 is an inhibitor of protein arginine methyltransferase 5 (PRMT5, IC50 = 0.14 nM). It inhibits the growth of various cancer cells in vitro and reduces tumor growth in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) mouse xenograft models.Formal Name:...
Keywords: (1S,2R,3S,5R)-3-[2-(2-amino-3-bromo-7-quinolinyl)ethyl]-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1,2-cyclopentanediol
Application: PRMT5 inhibitor
CAS 2086772-26-9
MW: 483.4 D
From 145.00€ *
Review