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Item number: Cay18445-1

Rp-8-pCPT-Cyclic GMPS is a stable, cell-permeable cGMP analog that competitively inhibits cGMP-dependent protein kinases (cGKs), including cGK Ialpha and cGK II (IC50s = 18.3 and 0.16 µM, respectively). The pCPT (p-chlorophenylthio) group at the 8-position of the purine increases both enzyme affinity and membrane...

Keywords:	Rp-8-pCPT-cGMPS, 8-[(4-chlorophenyl)thio]-cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate] guanosine, monosodium salt
Application:	Cell-permeable cGMP analog, Competetive cGMP-dependent protein kinase inhibitor
CAS	208445-07-2
MW:	525.9 D

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