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Item number: TGM-T6287-100mg

Description: Tariquidar (XR9576)(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines. Target: P-gp. Smiles: COc1cc2CCN(CCc3ccc(NC(=O)c4cc(OC)c(OC)cc4NC(=O)c4cnc5ccccc5c4)cc3)Cc2cc1OC. References: Martin C, et al. Br J Pharmacol, 1999,...

Keywords:	XR9576
Application:	Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243)
CAS	206873-63-4
MW:	646.73 D

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Tariquidar

Item number: Cay24180-100

Tariquidar is an anthranilic acid derivative that binds to P-glycoprotein (Kd = 5.1 nM) and inhibits transport activity. It inhibits transport of vinblastine (Cay-11762) and paclitaxel (Cay-10461) in multidrug resistant CHrB30 cells, increasing the steady state accumulation to non-P-glycoprotein-expressing multidrug...

Keywords:	XR9576,...
Application:	P-Glycoprotein inhibitor
CAS	206873-63-4
MW:	646.7 D

From 82.00€ *

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