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XL413 (hydrochloride)
XL413 (hydrochloride)

Item number: Cay24906-25

XL413 is a potent inhibitor of Cdc7 (IC50 = 3.4 nM). It is >60, >10, and >300-fold selective for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively. XL413 inhibits the growth of MDA-MB-231T and COLO 205 cells (IC50s = 118 and 140 nM, respectively). It inhibits Cdc7-specific phosphorylation of...
Keywords: 8-chloro-2-(2S)-2-pyrrolidinyl-benzofuro[3,2-d]pyrimidin-4(3H)-one, monohydrochloride
Application: Cdc7 inhibitor
CAS 2062200-97-7
MW: 326.2 D
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