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Item number: Cay16222-50

Pimozide is a dopamine receptor antagonist (Kis = 2.4, 0.3, and 1.8 nM for D2, D3, and D4 receptors, respectively). It also binds to eight additional receptors (Kds = 25-3,100 nM for the human receptors) and inhibits the voltage-gated sodium channel Nav1.2 and the voltage-gated potassium channel Kv11.1 (IC50s = 42...

Keywords:	NSC 170984, R 6238, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Application:	Dopamine D2/D3-receptor antagonist
CAS	2062-78-4
MW:	461.6 D

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Pimozide

Item number: TGM-T2546-1mL

Description: Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of the motor and...

Keywords:	R6238
Application:	Targets dopamine receptor D2 (DRD2)
CAS	2062-78-4
MW:	461.55 D

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