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XMU-MP-1
XMU-MP-1

Item number: TGM-T4212-2mg

Description: XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. Target: Hippo pathway. Smiles: CN1c2ccsc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12. References: Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med....
Application: STK3 / STK4 inhibitor
CAS 2061980-01-4
MW: 416.48 D
From 48.00€ *
Review
XMU-MP-1
XMU-MP-1

Item number: Cay22083-1

XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2...
Keywords: 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-benzenesulfonamide
Application: STK3 / STK4 inhibitor
CAS 2061980-01-4
MW: 416.5 D
From 35.00€ *
Review