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Item number: TGM-T11822-100mg

Description: LAU159 is a functionally selective positive alpha1beta3 GABA(A) receptor modulator (EC50: 2.2 µM). Target: GABA Receptor. Smiles: O=C1C=2C(C=3C(NC2)=CC=C(Cl)C3)=NN1C4=CC(OC)=CC=C4. References: Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA...

Application:	Positive alpha6beta3gamma2 GABAA receptor modulator
CAS	2055050-87-6
MW:	325.75 D

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LAU-159

Item number: Cay26336-1

LAU-159 is a positive allosteric modulator (PAM) of alpha6beta3gamma2 subunit-containing GABAA receptors. It selectively increases GABA-induced currents in X. laevis oocytes expressing alpha6beta3gamma2 over alpha1beta3gamma2, alpha2beta3gamma2, alpha3beta3gamma2, alpha4beta3gamma2, and alpha5beta3gamma2...

Keywords:	8-chloro-2,5-dihydro-2-(3-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one
Application:	Positive alpha6beta3gamma2 GABAA receptor modulator
CAS	2055050-87-6
MW:	325.8 D

From 35.00€ *

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