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GSK963
GSK963

Item number: Cay39900-10

GSK963 is an inhibitor of receptor-interacting serine/threonine kinase 1 (RIPK1). It is selective for RIPK1 with less than 50% inhibition of 339 kinases in a panel at 10 µM. Unlike the RIPK1 inhibitor necrostatin-1 (Cay-11658), GSK963 is inactive against indolamine-2,3-dioxygenase (IDO). GSK963 inhibits necroptosis...
Keywords: 1-[(5S)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-1-propanone
Application: RIPK1 inhibitor
CAS 2049868-46-2
MW: 230.3 D
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