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GSK963
Item number: TGM-T5054-100mg
Description: GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM). Target: RIP kinase. Smiles: CC(C)(C)C(=O)N1N=CC[C@H]1c1ccccc1. References: Berger SB, et al. Characterization of GSK'963: a structurally distinct, potent and selective inhibitor of RIP1 kinase. Cell...
| Keywords: | GSK963 (Racemate) |
| Application: | RIPK1 inhibitor |
| CAS | 2049868-46-2 |
| MW: | 230.31 D |
From 31.00€
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GSK963
Item number: Cay39900-10
GSK963 is an inhibitor of receptor-interacting serine/threonine kinase 1 (RIPK1). It is selective for RIPK1 with less than 50% inhibition of 339 kinases in a panel at 10 µM. Unlike the RIPK1 inhibitor necrostatin-1 (Cay-11658), GSK963 is inactive against indolamine-2,3-dioxygenase (IDO). GSK963 inhibits necroptosis...
| Keywords: | 1-[(5S)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-1-propanone |
| Application: | RIPK1 inhibitor |
| CAS | 2049868-46-2 |
| MW: | 230.3 D |
From 111.00€
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