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Item number: Cay28875-1

Filgotinib-d4 is intended for use as an internal standard for the quantification of filgotinib (Cay-17669) by GC- or LC-MS. Filgotinib is a JAK1 inhibitor (IC50 = 10 nM). It is selective for JAK1 over JAK3 (IC50 = 810 nM) but also inhibits JAK2 and tyrosine kinase 2 (Tyk2, IC50s = 28 and 116 nM, respectively), as...

Keywords:	GLPG0634-d4,...
Application:	GC-MS, LC-MS, internal standard, quantification, JAK1 inhibitor
CAS	2041095-50-3
MW:	429.5 D

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