2 products were found matching "2029049-79-2"!

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Item number: TGM-T13774-100mg

Description: ML390 exerts its potent differentiation effect on multiple leukemia models. Target: Dehydrogenase, Others. Smiles: FC(F)(F)Oc1ccc(cc1)C(=O)NCCC(=O)N[C@@H]1CCCc2ccccc12. References: Sykes DB et al. Discovering Small Molecules that Overcome Differentiation Arrest in Acute Myeloid Leukemia. National...

Application:	DHODH inhibitor
CAS	2029049-79-2
MW:	406.4 D

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ML-390

Item number: Cay21395-10

ML-390 is an inhibitor of dihydroorotate dehydrogenase (DHODH), the enzyme that converts dihydroorotate to orotate during de novo pyrimidine synthesis. In acute myeloid leukemia, leukemic myeloblast development is halted at an immature stage leading to perpetual self-renewal rather than differentiation. ML-390...

Keywords:	N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethoxy)-benzamide
Application:	DHODH inhibitor
CAS	2029049-79-2
MW:	406.4 D

From 66.00€ *

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