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Item number: Cay21546-50

Safinamide is an inhibitor of monoamine oxidase B (MAO-B, IC50 = ~0.1 µM). It is selective for MAO-B over MAO-A (IC50 = >10 µM). It also inhibits radioligand binding to sodium channel binding site 2, sigma-1, and sigma-2 receptors in rat brain membranes (IC50s = 8.2, 0.019, and 1.59 µM, respectively). Safinamide...

Keywords:	EMD 1195686, FCE 26743, NW-1015, PNU-151774E, 2S-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide,...
Application:	Reversible MAO-B inhibitor
CAS	202825-46-5
MW:	398.4 D

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