2 products were found matching "202592-23-2"!
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JQ-1 (carboxylic acid)
Item number: TGM-T5443-100mg
Description: JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2). Target: Epigenetic Reader Domain. Smiles: CC=1C2=C(N3C([C@H](CC(O)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C. References: Rosner M , Hengstschl?Ger M . Targeting Epigenetic Readers in Cancer[J]. New...
| Keywords: | JQ-1 carboxylic acid |
| Application: | BET family protein inhibitor |
| CAS | 202592-23-2 |
| MW: | 400.88 D |
From 63.00€
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(+)-JQ1 (free acid)
Item number: Cay9002910-1
(+)-JQ1 (free acid) is an inhibitor of bromodomain and extra terminal domain (BET) family proteins (Kds = 128, 59.5, 49.0, and 190 nM for JQ1 binding to bromodomains of BRD2, BRD3, BRD4, and BRDT, respectively), blocking their interaction with acetylated histones. Enantiomerically pure (+)-JQ1 (Cay-11187) binds to...
| Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid |
| Application: | BET family protein inhibitor |
| CAS | 202592-23-2 |
| MW: | 400.9 D |
From 74.00€
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