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JANEX-1
JANEX-1

Item number: TGM-T2045-100mg

Description: JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 µM), little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases. Target: JAK. Smiles: COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC. References: Sudbeck EA, et al....
Keywords: Jak3 inhibitor I, WHI-P131
Application: JAK3 inhibitor
CAS 202475-60-3
MW: 297.31 D
From 38.00€ *
Review
WHI-P131
WHI-P131

Item number: Cay10011246-10

Janus kinase 3 (JAK3) is a cytoplasmic protein tyrosine kinase that functions in the initiation of cytokine-triggered signal transduction by catalyzing the phosphorylation of signal transduction and activators of transcription (STATs). JAK3 is abundantly expressed in normal lymphoid cells as well as human...
Keywords: Janex 1, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Application: JAK3 inhibitor
CAS 202475-60-3
MW: 297.3 D
From 43.00€ *
Review
WHI-P131
WHI-P131

Item number: LKT-W2933.250

JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion. Increases survival in a mouse ALS model.
Keywords: JANEX-1, 4-((4'-hydroxyphenyl)amino)-6,7-dimethoxyquinazoline
Application: JAK3 inhibitor
CAS 202475-60-3
MW: 333,77 D
From 202.00€ *
Review