Description: m-3M3FBS is a phospholipase C (PLC) activator. Target: Apoptosis, Phospholipase. Smiles: Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc1cccc(c1)C(F)(F)F. References: Bae YS, et al. Identification of a compound that directly stimulates phospholipase C activity. Mol Pharmacol. 2003,63(5):1043-1050.

m-3M3FBS is an activator of phospholipase C (PLC) that stimulates superoxide generation, increase in cytoplasmic calcium, and inositol phosphate formation in human neutrophils when used at a concentration of 15-50 µM. It stimulates cytoplasmic calcium increases in several cell lines and, at 25 µM in vitro, promotes...

m-3M3FBS is a cell permeable and specific activator of phospholipase C (PLC) that has been shown to stimulate the PLC-mediated intracellular Ca2+ release, inositol phosphates production and superoxide generation in various cell types. It activates all PLC isotypes (beta2, beta3, gamma1, gamma2 and delta1) in vitro,...