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ML329
Item number: TGM-T4028-100mg
Description: ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity. Target: TRP/TRPV Channel. Smiles: NS(=O)(=O)c1ccc(NC2=CC(=O)c3ccccc3C2=O)cc1. References: Faloon PW, et al. A Small Molecule Inhibitor of the MITF Molecular Pathway. Probe Reports from the NIH Molecular Libraries Program...
| Application: | MITF inhibitor |
| CAS | 19992-50-8 |
| MW: | 328.34 D |
From 48.00€
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ML-329
Item number: Cay22481-5
ML-329 is an inhibitor of the microphthalmia-associated transcription factor (MITF) pathway with an IC50 value of 1.2 µM for promoter activity of the MITF target gene TRPM-1. It is selectively cytotoxic to the SK-MEL-5 and MALME-3M MITF-dependent melanoma cell lines over A375 MITF-independent cells (IC50s = 0.1,...
| Keywords: | 4-[(1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino]-benzenesulfonamide |
| Application: | MITF inhibitor |
| CAS | 19992-50-8 |
| MW: | 328.3 D |
From 46.00€
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