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Item number: Cay39739-10

Lixisenatide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and a derivative of exendin-4 (48-86) amide (Cay-11096). It binds to CHO-K1 cells expressing human GLP-1R (IC50 = 1.4 nM). Lixisenatide (100 pM) inhibits Il-1beta- and IFN-gamma-induced apoptosis in INS-1 rat pancreatic beta-cells. It lowers...

Keywords:	AVE-0010, ZP10A
Application:	GLP-1R agonist, hypoglycemic agent
CAS	1997361-87-1
MW:	4858.5 D

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