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Item number: Cay20473-1

CP-392,110 is an AMPA receptor antagonist. It inhibits AMPA receptor-mediated calcium uptake in rat cerebellar neurons (IC50 = 74 nM). CP-392,110 inhibits seizures induced by pentylenetetrazol (Cay-18682) or AMPA (Cay-14571) in mice with ID50 values of 3.8 and 3.6 mg/kg, respectively.Formal Name:...

Keywords:	3-(2-chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone, (2Z)-2-butenedioate
Application:	Noncompetitive NMDA receptor NR2C/D antagonist
CAS	199656-46-7
MW:	579 D

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CP-465022 (maleate)

Item number: TGM-T21875-10mg

Description: CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity, effectively countering the Kainate-induced response in rat cortical neurons with an IC50 of 25 nM, making it a valuable instrument for studying the involvement of AMPA receptors in various...

CAS	199656-46-7
MW:	579.02 D

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