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Merimepodib
Item number: TGM-T3444-100mg
Description: Merimepodib (VX-497) is a novel, noncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH). Target: HBV, HCV Protease, Antiviral, Dehydrogenase. Smiles: COc1cc(NC(=O)Nc2cccc(CNC(=O)O[C@H]3CCOC3)c2)ccc1-c1cnco1. References: Jain J, et al. VX-497: a novel, selective IMPDH inhibitor and...
| Keywords: | VX-497, VI-21497 |
| Application: | Targets IMP dehydrogenase [EC:1.1.1.205] (IMPDH, guaB) |
| CAS | 198821-22-6 |
| MW: | 452.46 D |
From 39.00€
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Merimepodib
Item number: Cay29351-5
Merimepodib is an inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH, Kis = 7 and 10 nM for IMPDH type I and type II, respectively) with antiviral and immunosuppressant activities. It reduces Ebola, Lassa, chikungunya, Junin, and Zika virus titers in vitro and inhibits Zika virus replication in Huh7 cells...
| Keywords: | VX-497, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-carbamic acid,... |
| Application: | IMPDH inhibitor |
| CAS | 198821-22-6 |
| MW: | 452.5 D |
From 43.00€
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