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Item number: TGM-T4307-100mg

Description: PF-06840003 (EOS200271) is a specific and orally active IDO-1 inhibitor. Target: IDO, Indoleamine 2,3-Dioxygenase (IDO). Smiles: Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1. References: Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune...

Keywords:	EOS200271, PF 06840003
Application:	IDO-1 inhibitor
CAS	198474-05-4
MW:	232.21 D

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EOS200271

Item number: Cay25003-5

EOS200271 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1, IC50 = 0.15 µM for the human enzyme). It is selective for IDO-1 over IDO-2 up to a concentration of 200 µM for the human recombinant enzymes. EOS200271 inhibits IDO-1-mediated production of kynurenine induced by IFN-gamma in HeLa cells (IC50 = 1.8...

Keywords:	PF-06840003, 3-(5-fluoro-1H-indol-3-yl)-2,5-pyrrolidinedione
Application:	IDO-1 inhibitor
CAS	198474-05-4
MW:	232.2 D

From 35.00€ *

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