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Trilaciclib hydrochloride
Item number: TGM-T13202-100mg
Description: Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6). Target: CDK. Smiles: Cl.Cl.CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1. References: Bisi JE, et al. Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction...
| Keywords: | G1T28 hydrochloride |
| Application: | Cdk4 / Cdk6 inhibitor |
| CAS | 1977495-97-8 |
| MW: | 519.47 D |
From 32.00€
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Trilaciclib (hydrochloride)
Item number: Cay37297-5
Trilaciclib is an inhibitor of cyclin-dependent kinase 4 (Cdk4)/cyclin D1 and Cdk6/cyclin D3 (IC50s = 1 and 4 nM, respectively). It is selective for Cdk4/cyclin D1 and Cdk6/cyclin D3 over Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, Cdk5/p35, Cdk7/cyclin H/Mat1, and Cdk9/cyclin T (IC50s = 1,290, 2,510, 1,710, 1,240,...
| Keywords: | G1T28,... |
| Application: | Cdk4 / Cdk6 inhibitor |
| CAS | 1977495-97-8 |
| MW: | 519.5 D |
From 54.00€
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