2 products were found matching "1976038-41-1"!
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TP-008
Item number: Cay41367-1
TP-008 is an inhibitor of activin receptor-like kinase 4 (ALK4) and ALK5, also known as TGF-beta receptor type 1 (TGF-betaRI, IC50s = 113 and 343 nM, respectively). It is selective for ALK4 and ALK5 over a panel of 467 kinases at 1 µM. TP-008 inhibits ALK4 or ALK5 signaling in a reporter assay using HEK293 cells...
| Keywords: | 1-[2-(5-chloro-2-fluorophenyl)-5-methyl-4-pyridinyl]-1,2-dihydro-2-oxo-3H-imidazo[4,5-c]pyridine-3-acetamide |
| Application: | ALK4 / ALK5 inhibitor |
| CAS | 1976038-41-1 |
| MW: | 411.8 D |
From 48.00€
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TP-008
Item number: TGM-T13139-100mg
Description: TGFbetaRI-IN-2 is a selective, potent and orally active inhibitor of (Activin-Like Kinase 5) ALK 5(pIC50 and pEC50 values of 7.6 and 6.63, respectively). Target: Others. Smiles: O=C1N(C=2C(N1CC(N)=O)=CN=CC2)C=3C=C(N=CC3C)C4=C(F)C=CC(Cl)=C4. References: Wang H, et al. Design, synthesis and optimization...
| Keywords: | TGFbetaRI-IN-2 |
| CAS | 1976038-41-1 |
| MW: | 411.82 D |
From 1,520.00€
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