2 products were found matching "192705-79-6"!
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PD-166866
Item number: TGM-T3492-100mg
Description: PD-166866 is a selective FGFR tyrosine kinase inhibitor. Target: Autophagy, FGFR. Smiles: COc1cc(OC)cc(c1)-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C. References: Risuleo G, et al. J Exp Clin Cancer Res. 2009, 28:151.
| Keywords: | PD166866 |
| Application: | FGFR1 inhibitor |
| CAS | 192705-79-6 |
| MW: | 396.44 D |
From 36.00€
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PD 166866
Item number: Cay22464-5
PD 166866 is a potent inhibitor of fibroblast growth factor receptor 1 (FGFR1, IC50 = 52.4 nM, Ki = 45.2 nM). It is selective for FGFR1 over PDGFR, EGFR, C-SRC, MEK, PKC, insulin receptor tyrosine kinase, and CDK4 (IC50s = >50 µM). PD 166866 inhibits FGFR1 autophosphorylation in NIH3T3 and L6 cells (IC50s = 10.8 and...
| Keywords: | N-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea |
| Application: | FGFR1 inhibitor |
| CAS | 192705-79-6 |
| MW: | 396.4 D |
From 44.00€
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