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Tipifarnib
Tipifarnib

Item number: TGM-T6271-10mg

Description: Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this...
Keywords: Zarnestra, R115777, IND 58359
Application: Antineoplastic
CAS 192185-72-1
MW: 489.4 D
From 34.00€ *
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Tipifarnib
Tipifarnib

Item number: Cay11747-5

Tipifarnib is a nonpeptidomimetic, CAAX-competitive inhibitor of farnesyltransferase (IC50 = 0.86 nM). It prevents farnesylation of Ras GTPases and has shown potent efficacy in various in vitro and in vivo tumor models.Formal Name:...
Keywords: R 115777, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
Application: CAAX-competitive farnesyltransferase inhibitor, Ras GTPase farnesylation inhibitor
CAS 192185-72-1
MW: 489.4 D
From 60.00€ *
Review