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LY3295668
LY3295668

Item number: Cay27914-1

LY3295668 is an inhibitor of Aurora A kinase (IC50 = 2 phase in HeLa cells (IC50 = 108 nM). In vivo, LY3295668 (40 mg/kg per day) decreases tumor volume in a patient-derived xenograft (PDX) mouse model of small cell lung cancer.Formal Name:...
Keywords: AK-01,...
Application: Aurora A kinase inhibitor
CAS 1919888-06-4
MW: 490 D
From 103.00€ *
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LY3295668
LY3295668

Item number: TGM-T15815-100mg

Description: LY3295668 (AK-01) is a selective inhibitor of Aurora A, with Ki values of 0.8 nM for Aurora A and 1038 nM for Aurora B. Target: Aurora Kinase. Smiles: C[C@@H]1C[C@@](Cc2nc(Nc3cc(C)[nH]n3)ccc2F)(CCN1Cc1cccc(Cl)c1F)C(O)=O. References: Gong X, et al. Aurora-A kinase inhibition is synthetic lethal with loss...
Keywords: AK-01
CAS 1919888-06-4
MW: 489.95 D
From 142.00€ *
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