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Item number: TGM-T4280-100mg

Description: Gcase activator 1 (LTI-291) is a glucocerebrosidase (Gcase) activator. Target: Glucosidase. Smiles: CCCCCO[C@H]1CC[C@@H](CC1)NC(=O)c1cnn2c(C)cc(C)nc12. References: Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO...

Keywords:	LTI291, LTI-291, LTI 291
Application:	GCase allosteric activator
CAS	1919820-28-2
MW:	358.48 D

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LTI-291

Item number: Cay34305-5

LTI-291 is a CNS-penetrant allosteric activator of glucocerebrosidase (GCase). It increases the activity of wild-type human GCase by 25 and 130% when used at concentrations of 0.1 and 1 µM, respectively.Formal Name: 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-pyrazolo[1,5-a]pyrimidine-3-carboxamide. CAS Number:...

Keywords:	5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-pyrazolo[1,5-a]pyrimidine-3-carboxamide
Application:	GCase allosteric activator
CAS	1919820-28-2
MW:	358.5 D

From 133.00€ *

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