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eCF506
eCF506

Item number: Cay19959-1

eCF506 is an inhibitor of Src kinases (IC50s = 50 = 479 nM), as well as KIT, mTOR, PDGFRalpha, and RET (IC50s = >100 µM for all). eCF506 completely inhibits phosphorylation of Src and FAK, a downstream Src substrate, in MCF-7 and MDA-MB-231 cells when used at a concentration of 100 nM. It also inhibits proliferation...
Keywords: N-[4-[4-amino-1-[2-[4-(dimethylamino)-1-piperidinyl]ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-carbamic...
Application: Src / Fyn / Yes inhibitor
CAS 1914078-41-3
MW: 510.6 D
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