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K-7174 (hydrochloride)
K-7174 (hydrochloride)

Item number: Cay32773-10

K-7174 is a 20S proteasome inhibitor. It inhibits the beta1, beta2, and beta5 catalytic subunits of the 20S proteasome when used at a concentration of 5 µM. K-7174 (10 µM) reduces TNF-alpha- or IL-1beta-induced adherence of U937 monocytes to human umbilical vein endothelial cells (HUVECs) in a co-culture model of...
Keywords: hexahydro-1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]-1H-1,4-diazepine, dihydrochloride
Application: 20S proteasome inhibitor
CAS 191089-60-8
MW: 641.7 D
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