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Item number: Cay41112-10

L-168,049 is a glucagon receptor (GCGR) antagonist (IC50s = 3.7 and 179 nM in the absence and presence of MgCl2, respectively). It prevents glucagon-induced increases in IL-1beta and IL-6 levels in, and levels secreted from, HepG2 cells when used at a concentration of 3.7 nM. L-168,049 inhibits glucagon-induced...

Keywords:	GCGR Antagonist II, Glucagon Receptor Antagonist II,...
Application:	GCGR antagonist
CAS	191034-25-0
MW:	467.8 D

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