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Item number: Cay23942-1

Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases µ-calpain (calpain-1, IC50 = 7.5 nM) and m-calpain (calpain-2, IC50 = 78 nM). It also inhibits cathepsins B and L (IC50s = 15 and 1.6 nM, respectively). It is selective for these calpains and cathepsins over other cysteine and serine...

Keywords:	SJA 6017, 2S-[[(4-fluorophenyl)sulfonyl]amino]-N-[(1S)-1-formyl-3-methylbutyl]-3-methyl-butanamide
Application:	Calpain-1/-2 inhibitor
CAS	190274-53-4
MW:	372.5 D

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