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Item number: Cay22289-10

Cilengitide is a cyclo-(Arg-Gly-Asp-D-Phe-Val) (cRGDfV) peptide and integrin alphaVbeta3 receptor antagonist. It inhibits adhesion and induces apoptosis of U87MG and U373MG malignant glioma (MG) cells, but not U251MG cells that lack the integrin alphaVbeta3 receptor, in vitro at a concentration of 20 µg/ml....

Keywords:	EMD 121974, cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
Application:	Integrin alphaVbeta3 receptor antagonist
CAS	188968-51-6
MW:	588.7 D

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Cilengitide

Item number: TGM-T2494-100mg

Description: Cilengitide (EMD 121974) is a potent integrin inhibitor for the alphavbeta3/5 receptor (IC50: 4.1/79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa. Target: Integrin, Autophagy. Smiles:...

Keywords:	EMD 121974
Application:	Angiogenesis inhibitor, Integrin antagonist
CAS	188968-51-6
MW:	588.66 D

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