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HX 531
Item number: Cay20762-1
HX 531 is an antagonist of the retinoid X receptor (RXR) with an IC50 value of 18 nM that inhibits 9-cis retinoic acid (Cay-14587)-induced transactivation of RXR. It has been shown to reduce triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice on a high fat diet.Formal Name:...
| Keywords: | 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)-benzoic acid |
| Application: | RXR antagonist |
| CAS | 188844-34-0 |
| MW: | 483.6 D |
From 43.00€
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HX 531
Item number: TGM-T22843-10mg
Description: HX 531 is a potent antagonist of the retinoid X receptor with an IC50 value of 18 nM. Target: Retinoid Receptor. Smiles: CN1c2ccc(cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C)[N+]([O-])=O. References: Bradley SM, Chan PS, Spertus JA, Kennedy KF, Douglas PS, Patel MR, Anderson HV, Ting HH,...
| CAS | 188844-34-0 |
| MW: | 483.56 D |
From 39.00€
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