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Item number: TGM-T6811-100mg

Description: CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor. Target: Histone Acetyltransferase, Epigenetic Reader Domain. Smiles: C[C@@H]1CC(=O)Nc2cccc(-c3ccc4n(C)nc(-c5cnn(C)c5)c4c3)c2N1. References: Taylor AM, et al. ACS Med Chem Lett. 2016, 7(5):531-6.

Keywords:	CPI 637
Application:	CREB-binding protein / Histone acetyltransferase p300 inhibitor
CAS	1884712-47-3
MW:	386.45 D

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CPI-637

Item number: Cay23500-1

CPI-637 is an inhibitor of cyclic-AMP response element binding protein (CBP) and adenoviral E1A binding protein of 300 kDa (EP300), a homologous pair of bromodomain-containing proteins (IC50s = 30 and 51 nM in a time-resolved-FRET (TR-FRET) assay). It is selective for CBP and EP300 over the BET family of...

Keywords:	(4R)-1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-benzodiazepin-2-one
Application:	CREB-binding protein / Histone acetyltransferase p300 inhibitor
CAS	1884712-47-3
MW:	386.5 D

From 44.00€ *

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