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NI-57
Item number: Cay17662-1
The bromodomain and PHD finger-containing (BRPF) proteins are scaffolding components of chromatin-binding MOZ/MORF histone acetyltransferase complexes, which have activity as transcriptional regulators. BRPF1 (BR140 or Peregrin) is important for maintaining Hox gene expression and the development of multiple...
| Keywords: | 4-cyano-N-(1,2-dihydro-1,3-dimethyl-2-oxo-6-quinolinyl)-2-methoxy-benzenesulfonamide |
| Application: | BRPF bromodomain inhibitor |
| CAS | 1883548-89-7 |
| MW: | 383.4 D |
From 44.00€
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NI-57
Item number: BPS-82069
NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI-57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI-57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced...
| Keywords: | NI57, NI 57, |
| Application: | BRPF bromodomain inhibitor |
| CAS | 1883548-89-7 |
| MW: | 383,4 D |
901.00€
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