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ML179
Item number: TGM-T8954-100mg
Description: ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM. Target: Others. Smiles: FC(F)(F)c1cccc(c1)N1CCN(CC1)c1cc(=O)n(C2CCCCC2)c(=O)[nH]1. References: Busby S , Nuhant P , Ca Meron M , et al. Discovery of Inverse Agonists for the Liver Receptor...
| Keywords: | ML-179 |
| Application: | NR5A2 inverse agonist |
| CAS | 1883548-87-5 |
| MW: | 422.44 D |
From 51.00€
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ML-179
Item number: Cay15180-10
ML-179 is a potent inverse agonist of liver receptor homolog-1 (LRH-1) (IC50 = 320 nM) with maximum efficacy of 40% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the...
| Keywords: | CID-45100448, 3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-2,4(1H,3H)-pyrimidinedione |
| Application: | NR5A2 inverse agonist |
| CAS | 1883548-87-5 |
| MW: | 422.4 D |
From 60.00€
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